From a correspondent

 I first became interested in the Lucy Letby (LL) case when my wife referred me to a 10 hour podcast entitled: “The Case of LL; The Facts – Crime Scene 2 Court Room”, https://www.youtube.com/watch?v=_OA0ukO7D7c. Since, I have searched for further background to this case. Richard Gill’s website raises issues around imbalance between the prosecution and the defence, or lack of it! Also, there was toxic atmosphere at the Countess of Chester (CC) neonatal unit and LL reported problems. I worked for over 25 years anaesthetizing children down to 500g, in addition to adult anaesthesia, as well as expert witness experience. I also spent 6 months attached to a Neonatal Unit. The question of whether LL committed the alleged crimes is a difficult one to answer as (a) no one actually witnessed her doing the alleged crimes, (b) there is no obvious motive, (c) the actions would be very hard to achieve and (iv) there are other alternative explanations that were not explored by the court case, or at least the 10 hour transcript.

The Countess of Chester baby unit: The main purpose of the unit was a nursey to look after and feed babies too small and fragile to leave hospital, born at the CC. There was a small 4 bedded-neonatal unit in addition to the 4 nursery rooms. LL probably wanted to gain neonatal experience hence her involvement with the 17 cited cases.

Neonates and vulnerability: Small preterm babies easily deteriorate and die. Their organs are still developing and without the advent of neonatal units in the 1980s most would die. It is only today that a baby born prematurely before 28 to 32 weeks has a good chance of survival.

Staffing levels, staff experience and standard of care: LL was only 25 years old at the time and had only been a neonatal nurse for a few years. That is not very long and she lacked experience! She still needed further training in Liverpool to advance her career. Yet, she seemed to be one of the most senior neonatal nurses (band 5) on the unit and nowhere in the transcript do we find an older, more senior or experienced colleague other than a charge nurse who managed the duties and was not hands on. Similarly, it appears that medical cover was by paediatricians who also covered the wards and there was no doctor solely on duty for the unit. Therefore, when compared to other bigger units (i.e. Alder-Hey) the level of care was limited, so it would not be surprising if a baby deteriorates, and that happens with “prems”, outcomes are not as good. So, the evidence suggests that the CC was not up to standard, and it was an overflow unit for Alder-Hey. The CC neonatal unit has since been closed down. So were the cited incidents and deaths really due to LL or a result of a poorly supported / under-funded unit looking after sick neonates that should have been elsewhere?

The prosecution case focused on a number of methods of harming babies allegedly used by LL: (i) Distending the stomach by giving too much feed or (ii) injecting air into the stomach, (iii) injecting air into the circulation causing sudden collapse, (iv) traumatising the airway and causing bleeding, (v) dislodged tracheal and chest tubes, and (vi) adding insulin to the intravenous feed. The discussion of the pathophysiology of these mechanisms was disjointed and difficult to follow. However, the connection of LL to the sudden deteriorations and deaths in 7 seemed very compelling. However, I have to take issue with a number of the prosecution’s assertions.

(i) Over-distending the stomach with feed to an extent to cause collapse and projectile vomiting. I don’t have any experience of tube feeding prems, but projectile vomiting can be a reaction to bad / infected milk? Was LL in hurry to feed the baby? I find it hard to believe this was an attempt at murder.

(ii) Most obvious was the air in the stomach and intestines at post mortem. LL must have injected air via the gastric feeding tube, or how else did it get there? Well anyone who works in theatre or resuscitation knows during mask ventilation, which all these babies had (i.e. Neopuff), that it is very easy to blow up the stomach and intestines with air / anaesthetic gases, especially if one’s technique is not perfect. I regularly had to pass a suction catheter to empty the stomach of gas at the start of surgery to deflate the stomach and improve ventilation. I even did a study on the carbon dioxide levels that often reached the level of expired gas. However, the role of the Neopuff as a potential cause was never mentioned. So what is more likely, LL injected the air or the air got there through resuscitative efforts by stressed staff.

(iii) Some of the babies suddenly collapsed and developed a strange rash on the abdomen. Some recovered rapidly. This was said to be due to LL injecting air into the circulation. Air was found to be in the blood vessels at post mortem in some deaths. The premature baby can revert to a foetal circulation (by passing the lungs) when they become unstable and this can take time to treat (revert back). Sometimes “persistent foetal circulation” manifests itself during anaesthesia until the ductus closes fully. Point not mentioned in the case but could explain the above. Also, chest compression would cause significant sucking in of air to the heart if intravenous access lines were left open to air during the resuscitation after injecting a drug (adrenaline). LL sent a Datex about a line being left uncapped by one of the doctors. So there are other explanations and mechanisms by which air could have entered the circulation.

(iv) One of the cases had trauma to oral airway and significant blood loss, I think this was one of the twins with Haemophilia, a blood clotting disorder. LL was accused of traumatising the airway. I cannot imagine how. The likely explanation would be repeated intubation attempts, not an attempt to murder the baby by LL. I recall up to seven attempts as the neonate was difficult to intubate!

(v) LL was also accused of dislodging an endotracheal tube and a chest drain which lead to deterioration in two patients. Preterm babies are very small, endotracheal tubes can easily move and become dislodged however carefully one secures them, particularly if the neck is flexed or extended! Similarly, with chest drains, the baby had bilateral drain presumably as a result of premature lungs, and one drain became dislodged / was not working and a third drain was needed. These things happen so just because LL was present does not automatically mean it was her fault. Then there was the incident with deliberate liver injury, which equally could have occurred during chest compressions by someone else?

(vi) The addition of insulin to intravenous feeds has already been mentioned by Gill from a biochemistry and reliability of blood test perspective. I don’t fully understand this one. One baby was receiving regular intravenous nutrition made up in sealed bags from pharmacy. The baby had unexplained hypoglycaemia. For three bags it persisted and when LL was not on duty the hypoglycaemia resolved. Blood were analysed insulin and C peptide. Hypoglycaemia is common in preterm babies because their mechanisms to maintain blood glucose levels are immature (i.e. glycogen stores in the liver). The child may have had an infection as Gill says there was virus circulating. That being said it difficult to image how LL managed to injected the correct and same amount of insulin into a sealed bag on three separate occasions. There is a rigid nursing protocol involving two nurses when a new bag is put up to maintain sterility. Then there was a further insulin contaminated Dextrose infusion in a second baby. BTW, LL was not the only nurse present for both these cases.

Hence, I find it very difficult to accept the verdict that Lucy Letby was responsible for all 7 deaths and a further 6 attempts at murder. I think that her case needs to be reviewed by someone with a better understanding of neonatal medicine and how a premature baby unit is run.

Signed Lester; 20.10.2023

The Timeline of the Conspiracy

The following text is taken from Science on Trial, https://www.scienceontrial.com/, I will later link to the precise location on that website, and find out if the author may be named.

After having read through multiple articles detailing the timeline of the circumstances behind of the allegations, I thought I’d provide a brief but detailed history of the sequence of events resulting in Miss Letby being arrested and charged. I’m sure many of you know this timeline already, hopefully there are more details here you will find interesting.  For those who don’t know the chronology, I hope the below is useful. That this was a fairly open conspiracy between senior consultants at the hospital, primarily Dr Stephen Brearey (he is in fact the architect) and Dr Ravi Jayaram, and later detectives at Cheshire Police assigned to the case titled ‘Operation Hummingbird’ is difficult to dispute. They’ve quite openly admitted it by clumsily showering praise on themselves following the trial in a bizarre attempt to characterise themselves as heroes. Although the record is fragmented and the sources are scattered, a reconstruction is possible nonetheless.

-On June 8 2015 Child A, a premature newborn twin, suddenly collapses on the neonatal unit. Dr Ravi Jayaram, who responds to the emergency alert, later testified that he noticed “pink patches, mainly on the torso, which seemed to appear and disappear and flit around. I had never seen anything like it before but my focus at the time was on ABC, airway, breathing, circulation.” He added: “I could not explain the sequence of events, why they had happened. I couldn’t explain why it had happened in the first place and couldn’t explain why the physiological responses to timely and appropriate interventions did not happen as they should have happened.” Dr Jayaram does not mention the skin discolouration in the clinical notes he made three hours after Child A died. He testified “I didn’t appreciate the clinical significance of this whatsoever”. When asked why he also failed to mention it to the coroner presiding over the inquest of Child A, Dr Jayaram replied: “My concluding remarks when I gave evidence is that I couldn’t explain how this had happened, It was not my job to say ‘it may have been this’ because at that time I had no evidence”.

-Around midnight on 9 June 2015, Child B’s blood/oxygen levels drop. She is blue, not breathing and limp. 

-In the early hours of 14 June 2015 Child C suddenly collapses. He is pronounced dead at 5:50am.

-On 21/22 June 2015, Child D collapses three times, the last one being fatal. Those present notice discolouration on the babie’s skin.

-Towards the end of June 2015, after Child D’s death, Dr Stephen Brearey notices that Lucy Letby is on shift for each instance of four collapses, three of them fatal, in the last two weeks. She is the only nurse present in each case. Dr Brearey shares this informal review with Dr Ravi Jayaram. He tells Dr Jayaram that nothing linked the deaths “other than one nurse”. The deaths are reported by consultants to hospital’s trust committee for serious incidents. The hospital classifies them as “medication errors” and not a “serious incident involving an unexpected death”. 

-By June 2015, Dr Brearey, Dr Jayaram and “other colleagues” all identify Miss Letby as a potential link. 

-On 29 June 2016 the entire consultant body at the hospital hold a meeting concerning the collapses. Air embolism is one of the topics discussed. That evening Dr Jayaram conducts a literature search and comes across the 1989 medical paper titled “Pulmonary Vascular Air Embolism In The Newborn”. Dr Jayaram will later testify to the court that the paper describes a series of accidental events of air embolism. The context within which the research paper studies air embolism is as an inadvertent complication of mechanical ventilation. Dr Jayaram emails links to the medical paper to colleagues the next day.

-On 2 July 2015, Dr Stephen Brearey, Eirian Powell, a nurse and ward manager responsible for the nursing staff on the neonatal unit, and Allison Kelly, director of nursing at the hospital hold a meeting. Lucy’s presence when the three deaths occurred is discussed. 

-By October 2015, seven infants have died in unusual circumstances. Dr Brearey openly suspects Miss Letby is harming children. Miss Letby will go on to be convicted for murdering five of these infants. The remaining two, despite being investigated by the police, were never bought to trial.

-On 23 October 2015 Eirian Powell emailed the findings of her own review of these collapses to Stephen Brearey. She states “I have devised a document to reflect the information clearly and it is unfortunate she [Miss Letby] is on [shift] – however each cause of death was different, some were poorly prior to their arrival on the unit and the other were ?NEC or gastric bleeding/congenital abnormalities. I have attached the document for your perusal”. 

-In February 2016 Dr Brearey orders a half-day thematic review into the deaths and collapses with the help of Consultant Neonatologist at Liverpool Women’s NHS Foundation Trust Dr Nimish Subhedar. It finds several common links in nine unusual deaths since June 2015. Four of these were never brought to trial.

-On February 15 2016, The report is sent to Ian Harvey, the hospital’s medical director and second in charge, and Allison Kelly. It includes a table of the nine deaths identified in the review, showing Miss Letby is on shift for each one. Dr Brearey requests an “urgent meeting”. Management determine Miss Letby’s presence is a coincidence. 

-On March 17 2016, Eirian Powell & Allison Kelly discuss via email how Miss Letby was a commonality in the deaths. 

-On April 7 2016, Eirian Powell moves Miss Letby to day shifts to support her wellbeing because she had been present for so many of the collapses.

-On April 9 2016, Child M suffers a dramatic drop in heart rate and breathing. This occurred during a day shift and is used to suggest that deaths and collapses “follow” Miss Letby.

-In May 2016, Dr Brearey emails Allison Kelly, flagging Miss Letby’s presence at the deaths and asking for a meeting. Allison Kelly fowards the email to Ian Harvey expressing alarm that a doctor was implicating a nurse. She tells Ian Harvey that there was no evidence but that a wider review might be needed. Allison Kelly asks senior nurse managers to examine any staffing trend linked to the deaths, adding that it was ”potentially very serious“. 

-On 11 May 2016 Dr Brearey and other doctors meet Kelly and Harvey to discuss their concerns about Miss Letby. The senior managers produce a two-page “assurance” document detailing why Miss Letby is not believed to be the cause of the unusual deaths. It suggested other NHS services may be to blame for the spike in deaths and that: “There is no evidence whatsoever against LL other than coincidence”. They agree to review all the deaths and keep Miss Letby on day shifts for three months. Dr Brearey feels his concerns have been dismissed.

-On 16 May 2016, a senior doctor tells Eirian Powell during a meeting: “You are harbouring a murderer”. 

-On 23 June 2016 newborn triplet, Child O, dies after a number of collapses. 

-On 24 June 2016 Child P, the brother of Child O, suffers an ‘acute deterioration’. He suffers a number of collapses and is finally pronounced dead at 4pm. The coroner later recorded the death as ‘prematurity’. The prosecution later claimed Miss Letby injected air into his stomach. Stephen Brearey calls hospital nursing director Karen Rees to express his concerns. He no longer wants Miss Letby working on the unit. Rees insists there is no evidence against Miss Letby and says she will take responsibility for allowing her to continue to work.

-In late June 2016 emails are exchanged between nurses, doctors and hospital executives. One of the doctors recommends calling the police. Ian Harvey replies to the chain saying concerns were being “discussed and actions taken”. 

Executive directors at the hospital meet and debate calling the police for the first time. They consider the impact of an investigation and arrest, and subsequent reputational issues and impact on the trust. They acknowledge the evidence is circumstantial and express their concerns about the unit’s leadership. They fear the doctors are carrying out a witch-hunt. The trust do not contact the police. 

The neonatal unit is downgraded to level 1 so that the sickest and most premature children are sent to neighbouring hospitals. Ian Harvey and Tony Chambers, the hospital’s chief executive, contacts the Royal College of Paediatrics and Child Health and asks them to review the neonatal unit’s service level. The hospital’s executives meet the doctors and tell them they considered contacting the police but decided to handle it in a different way. 

-By July 2016 mortality data shows there had been 14 neonatal deaths in just over a year. An internal review by the nursing director notes that higher acuity levels, higher activity and short staffing levels may have all contributed. It does not mention any concerns around any individual. Miss Letby is called to a meeting with a senior nurse and a HR Manager. She is told for the first time of her association with the infant deaths. She is visibly upset and distressed. The decision has been to place her under supervision, alongside other staff. 

-In mid-July 2016 Miss Letby is redeployed to the hospitals risk and patient safety office. Staff shortages on the neonatal unit meant supervision of her was not possible after all.

-In early September 2016, the RCPCH arrive and begin their investigation. Miss Letby is one of the first to be interviewed.

-On 7 September 2016 Miss Letby submits a formal grievance against the trust for victimisation and discrimination at being removed removed from the ward. This is after learning through her Royal College of Nursing representative of the concerns by doctors on the unit. 

–In October 2016 the RCPCH report back to Harvey and Chambers. They find that what had happened ”appears unusual and needs further inquiry to try to explain the cluster of deaths“. A draft version of the report is drawn up. It raises general concerns around short staffing and clininal practices. It notes an increased volume of cases with increased acuity levels, but states this was not significant enough to explain the high mortality rate. It also says there “no obvious factors which linked the deaths and that circumstances in the unit were not materially different from those which might be found in many other neonatal units”. However it recommends detailed case reviews are needed for each of the deaths, including examination of obstetric, pathology, nursing and post-mortem indicators. It also includes a confidential section linking the deaths with Miss Letby and the subjective concerns of Dr Stephen Brearey, the neonatal lead. This section is redacted from the version circulated to the board, the doctors and the bereaved parents.*

Ian Harvey contacts Dr Jane Hawdon, a neonatalogist, asking her to carry out a forensic review of each death. Hawdon produces a five page review but tells Harvey she did not have the time to conduct the thorough investigation the royal college had recommended. Nonetheless it cited four cases which could not be explained but would “potentially benefit from local forensic review as to circumstances, personnel etc.”

The executive managers meet again and agree that not calling the police the was the right decision as the doctors’ evidence was “unconvincing”.

-In November 2016 two and a half months have passed since Miss Letby’s grievance. During the investigation, Doctors who raised concerns about her causing harm to infants, including Brearey and Jayaram, were interviewed, with their union reps present, by an investigator. The investigation finds no evidence to justify calling in the police. Instead it finds the doctors are at fault for suspecting her of murder. ”This behaviour has resulted in you, a junior colleague and fellow professional, feeling isolated and vulnerable, putting your reputation in question,“ the grievance inquiry told Letby. ”This is unacceptable and could be viewed as victimisation“. 

-On 12 November 2016 HR prepare Miss Letby’s return to the neonatal unit.

-On 22 December 2016 Tony Chambers issues Miss Letby with a full apology on behalf of the hospital trust, and assures her family the doctors who had victimised her would be dealt with.

-In January 2017 the hospital board hold a meeting. Harvey states the RCPCH review found the incidents were down to issues of “leadership, escalation and timely intervention” and that it “does not highlight any single individual”.

In a separate meeting, Harvey and Chambers tell seven clinicians, including Brearey and Jayaram, that “things have been said and done that were below the values and standards of the trust.” Mediation between Miss Letby and both Brearey and Jayaram was demanded. They were told it would protect them from a referral to the General Medical Council (GMC), the doctors’ watchdog. The British Medical Association Rep advised them to write a letter of apology to Miss Letby. 

-In late January the doctors write to Harvey. They ask “what is the reason for the unexpected and unexplained deaths? What should we as paediatricians do now?”

-On 1 March 2017 the paediatricians write a letter of apology to Miss Letby. 

-In March 2017 the consultants seek external advice from the regional neonatal lead who agrees that several cases require further investigation. They meet again with Harvey and Chambers to ask police to investigate. At this point it was agreed. The high deaths and suspicions were raised with police through the local child death and overview panel. 

-On 27 April 2017 Detective Superintendent Paul Hughes meets Dr Brearey and Dr Jayaram at the Countess of Chester Hospital. The meeting proved decisive. Dr Jayaram said “the police, after listening to us for 10 minutes, realised this is something they had to be involved in”. Whether the name Lucy Letby was mentioned at this meeting or a little later is irrelevant. The next day Operation Hummingbird was launched, and more than a year later on 3 July 2018 Miss Letby was arrested. 

The most disturbing facts I came across while researching this piece was that two fundamentally vital pieces of  evidence cited in the trial by the prosecution, had long been prepared by the doctors before the name Dewi Evans became remotely connected.

(i) The table that showed Miss Letby on shift for all the collapses and deaths had already been built by Dr Stephen Brearey in February 2016.

(ii) The air embolus theory had already been determined as her modus operandi as early as June 2015. Dr Jayaram had been sitting on the 1989 paper since June 2015.

Furthermore whilst not discussed above, Dr Stephen Brearey just so happens to be the very doctor who finally finds the so-called ‘smoking gun’. On 13 February 2018 discovers the blood sample for Child F which apparently proves deliberate harm in the form of insulin poisoning. Incidentally, Vincent Marks is a Doctor of Medicine and Clinical Scientist who has conducted highly relevant research into the forensic aspects of hypoglycaemia. His works include: ‘Insulin Murders’, ‘Hypoglycemia: Accidents, Violence and Murder’. He claims that a fatal dose of insulin for an adult human being is around 1,000 units. Child F’s level was 4,657 units. 

*Redacted passages: “The neonatal lead [Stephen Brearey], in an effort to be thorough and explore all possibilities had identified that one nurse had been rostered on shift for all the deaths although the nurse had not always been assigned to care for that specific infant. Subsequently, the paediatric lead and all the consultant paediatricians had become convinced by the link. Although this was a subjective view with no other evidence or reports of clinical concerns about the nurse beyond this simple correlation an allegation was made to the Medical Director and Director of Nursing.

“On arriving for the visit the RCPCH Review team was told that the nurse had been moved to an alternative position around ten weeks previously without explanation nor any formal investigative process having been established. The Review team was told that the individual was an enthusiastic, capable and committed nurse who had worked on the unit for four years. She herself explained to the Review team that she was passionate about her career and keen to progress. She regularly volunteered to work extra shifts or change her shifts when asked to do so and was happy to work with her friends on the unit. The Directors understood there was nothing about her background that was suspicious; her nursing colleagues on the unit were reported to think highly of her and how she responded to emergencies and other difficult situations, especially when the transport team were involved. There were apparently no issues of competency or training, she was very professional and asked relevant questions, demonstrating an enthusiasm to lead along with a high level of professionalism.